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T0383 |
Fenspiride hydrochloride
|
Fenspiride HCl,Pneumorel,Fluiden,Decaspiride |
Adrenergic Receptor
,
PDE
,
Histamine Receptor
|
|
Fenspiride hydrochloride (Decaspiride) , an oxazolidinone spiro compound, is a drug used in the therapy of certain respiratory diseases. It is approved for use in Russia for the therapy of chronic and acute inflammatory ... |
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T0768 |
Oxolamine citrate
|
AF-438 citrate,SKF-9976 citrate |
Others
|
|
Oxolamine citrate (AF-438 citrate) is a cough suppressant that is able to be used as a generic drug in many jurisdictions. |
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T5449 |
Bamaquimast
|
L 0042,F 10126 |
Proton pump
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|
Bamaquimast (L 0042) is a proton pump inhibitor for the study of asthma-like immune system disorders and respiratory diseases. |
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T67815 |
Uk-50001
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|
PDE
|
|
uk-50001 is a phosphodiesterase (PDE) 4 inhibitor that can be used for many diseases, especially inflammation, allergies, respiratory diseases, disorders and conditions and wounds. |
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T15431 |
Nemiralisib
|
GSK2269557 (free base),GSK2269557 |
PI3K
|
|
Nemiralisib（GSK-2269557 free base） is an orally available, potent and specific PI3Kδ inhibitor with a pKi of 9.9.Nemiralisib is used for the treatment of respiratory diseases including chronic obstructive pulmonary disea... |
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T61239 |
GAL-021 sulfate
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|
Potassium Channel
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|
GAL-021 sulfate is a BKCa channel blocker that inhibits the analgesic effects of opioids and is used in the study of respiratory control diseases. |
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T21322 |
Mavelertinib
|
PF 06747775,PFE-X775,PF-06747775,PF-7775,PF 6747775,PF6747775 |
EGFR
|
|
Mavelertinib (PF-06747775) is an orally available, selective and potent EGFR tyrosine kinase (EGFR TKI) inhibitor with inhibitory effects on T790M/L858R and T790M/Del, and can be used in the study of oncology and respira... |
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T39719 |
Nrf2 activator-1
|
Nrf2 activator-1 |
Nrf2
|
|
Nrf2 activator-1 is a potent activator of NF-E2-related factor 2 (Nrf2).Nrf2 activator-1 can be used to study COPD and other respiratory diseases including asthma, acute lung injury (ALI), acute respiratory distress synd... |
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T9653 |
(E/Z)-Sivopixant
|
(E/Z)-S-600918 |
P2X Receptor
|
|
(E/Z)-Sivopixant ((E/Z)-S-600918)is a potent P2X3 receptor antagonist, IC50 = 4 nM. (E/Z)-Sivopixant can be used for respiratory diseases research. |
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T60522 |
Letosteine
|
Viscotiol |
Others
|
|
Letosteine (Viscotiol) is an orally active, effective, and safe expectorant that can be used in the study of acute or chronic respiratory diseases, for example, bronchopulmonary disease. Letosteine dissolves bronchial mu... |
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T68086 |
Imitrodast
|
|
Thrombin
|
|
Imitrodast is a small molecule thromboxane A2 synthase (TXA2 synthase) inhibitor for the treatment of immune system disorders, respiratory disorders, and cardiovascular diseases, and can be used in studies of arterial th... |
|
T6850L |
GSK2292767 FA
|
GSK2292767 FA(1254036-66-2 Free base) |
PI3K
|
|
GSK2292767 FA is a potent and selective inhibitor of PI3Kδ (pIC50 : 10.1).GSK2292767 FA is more than 500-fold more selective than other PI3K isoforms.GSK2292767 FA can be used in the study of respiratory diseases. |
|
T0920 |
Ambroxol
|
Ambroxolum,NA-872 |
P450
,
Autophagy
|
|
Ambroxol (NA-872) is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. The substance is a muco... |
|
T67385 |
Neratinib maleate
|
HKI-272 maleate |
EGFR
,
HER
|
|
Neratinib maleate (HKI-272 maleate) is an irreversible, orally active and highly selective inhibitor of HER2 and EGFR with IC50 values of 59 nM and 92 nM, respectively.Neratinib maleate has antitumor activity and can be ... |
|
T70402 |
LAS195319
|
|
|
|
LAS195319 is a potent and selective inhaled PI3Kδ Inhibitor (IC50 = 0.5 nM) for the Treatment of Respiratory Diseases. |
|
T10121 |
Substance P Receptor Antagonist 1
|
|
Others
|
|
Substance P Receptor Antagonist 1 has the potential function in gastrointestinal disorders, inflammatory diseases, respiratory, and central nervous system disorders. |
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T69786 |
GSK3491943
|
|
|
|
GSK3491943 is a potent TRPV4 inhibitor with IC50 = 3.2 nM. GSK3491943 is a potential agent for the treatment of heart failure and respiratory diseases. |
|
T39612 |
BTK-IN-5
|
|
|
|
BTK-IN-5 is a covalent inhibitor of Bruton's tyrosine kinase (BTK) designed for the treatment of medical conditions including cardiovascular diseases, respiratory diseases, inflammation, and diabetes. |
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T33282 |
Memotine HCl
|
UK-237101,UK-2371,UK 237101,UK 2371,UK2371 |
|
|
Memotine HCl has antiviral activity against respiratory tract infection and is used as a therapeutic agent for acute respiratory diseases. It is also a memo fracture in the form of hydrochloride, an isoquinoline, with an... |
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T30835 |
Cgp 45715A
|
Cgp45715A,Cgp-45715A |
|
|
CGP 45715A (irukostat) is a potent peptide-leukotriene antagonist used to treat respiratory diseases by antagonizing the bronchial constriction, mucus secretion, and inflammatory effects of these leukotrienes. |
|
T28250 |
ONO-6126
|
ONO6126,DE103,DE-103,DE 103 |
|
|
ONO-6126 has anti-inflammatory activity and can inhibit Phosphodiesterase and PDE4 in the treatment of respiratory diseases. |
|
T63658 |
JAK-IN-18
|
|
|
|
JAK-IN-18 is a potent inhibitor of JAK and can be used to study a variety of diseases, particularly eye, skin and respiratory diseases. |
|
T73250 |
JAK-IN-17
|
|
|
|
JAK-IN-17 is a potent inhibitor of JAK . JAK-IN-17 is useful for the research of multiple diseases, particularly ocular, skin, and respiratory diseases. |
|
T72105 |
BMS-433771 dihydrochloride hydrate
|
|
|
|
BMS-433771 dihydrochloride hydrate is a potent, orally active respiratory syncytial virus (RSV) inhibitor effective against both group A and B strains, demonstrating an average EC50 of 20 nM. It is utilized in researchin... |
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T16758 |
Rispenzepine
|
|
Others
|
|
Rispenzepine is a novel antagonist of muscarinic acetylcholine receptors (mAChRs), selectively targeting the M1 and M3 receptor subtypes, and can be used in the treatment of immune system disorders, infections, and respi... |
|
T9901A-016 |
TNM001
|
|
|
|
TNM001 is a fully human monoclonal antibody to RSV for the study of lower respiratory tract diseases due to RSV infection. |
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T60238 |
Acloproxalap
|
|
|
|
Acloproxalap is a quinoline-based aldehyde scavenger that can be used in studies of diseases with toxic aldehyde accumulation, such as inflammatory diseases of the eye and skin, respiratory diseases such as pneumonia, or... |
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T64312 |
Motugivatrep
|
|
|
|
Motugivatrep is a potent type 1 transient receptor potential (TRPV1) antagonist and has a broad role in the treatment of drug, urinary tract and respiratory diseases. |
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T69784 |
GSK3527497 HCl
|
|
|
|
GSK3527497 is a potent and selective inhibitor of Transient Receptor Potential Vanilloid‑4 (TRPV4) with IC50 = 12 nM) for the treatment of heart failure and respiratory diseases. GSK3527497 is a preclinical candidate sui... |
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T31396 |
Dexbrompheniramine maleate
|
D-Brompheniramine,Brompheniramine d-,Dexbrompheniraminum,Disophrol,Drixoral |
|
|
Dexbrompheniramine is an antihistamine with anticholinergic properties. It is used to treat allergic diseases such as hay fever or urticaria. It can compete with histamine for H1 receptor sites on effector cells of the g... |
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T63893 |
Adenylyl cyclase type 2 agonist-1
|
|
|
|
Adenylyl cyclase type 2 agonist-1 is a potent agonist of adenylyl cyclase type 2 (AC2) (EC50: 90 nM). It is a potential lead compound in the fight against respiratory diseases. |
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T11819 |
Lascufloxacin
|
KRP-AM1977X |
Others
|
|
Lascufloxacin, a potent and orally active fluoroquinolone antibacterial agent, holds potential for the treatment of various infectious diseases, including lower respiratory tract infections. It effectively inhibits infec... |
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T10892 |
CS-003 Free base
|
|
Neurokinin receptor
|
|
CS-003 free base (CS-003) is a triple tachykinin receptor antagonist with high affinity for human (neurokinin) NK1, NK2 and NK3 receptors, with Ki values of 2.3 nM and 0.54 nM, respectively And 0.74 nM. CS-003 free base ... |
|
T71291 |
EICAR
|
|
|
|
EICAR is a drug which acts as an inhibitor of the enzyme IMP dehydrogenase. It is a nucleoside derivative which has both anti-cancer and antiviral effects, and was originally developed for the treatment of leukemia, but... |
